Hello!

Neuropsychiatry team portal: www.eratne.net/portal

Website: www.neuropsychiatry.org.au
Twitter: www.twitter.com/NWMentalHealth
Publications: Full list on PubMed

The MiND Study – themindstudy.org

The Seminars in Neuropsychiatry: www.eratne.net/seminars

Neuropsychiatry Publications

Click here for the full list of publications on PubMed (currently only first author displays below, unfortunately)

• Recent research advances in young-onset dementia
  January 27, 2023 by Samantha M Loi
  PURPOSE OF REVIEW: Young-onset dementia (YOD) refers to a dementia for which symptom onset occurs below the age of 65. This review summarizes the recent literature in this area, focusing on updates in epidemiology, diagnosis and service provision.
• Understanding Clinician's Experiences with Implementation of a Younger Onset Dementia Telehealth Service
  November 26, 2022 by Aimee D Brown
  The successful implementation of telehealth services depends largely on clinician acceptance of telehealth as a viable healthcare option and their adoption of telehealth methods into their clinical practice. While growing research supports the feasibility of telehealth services, no research has evaluated clinicians' experiences during the implementation of a younger onset dementia telehealth service. Semi-structured group interviews were conducted with 7 metropolitan (hub) clinicians and 16…
• Heschl's gyrus duplication pattern and clinical characteristics in borderline personality disorder: A preliminary study
  November 21, 2022 by Tsutomu Takahashi
  Inter-individual variations in the sulco-gyral pattern of Heschl's gyrus (HG) might contribute to emotional processing. However, it remains largely unknown whether borderline personality disorder (BPD) patients exhibit an altered HG gyrification pattern, compared with healthy individuals, and whether such a brain morphological feature, if present, might contribute to their clinical characteristics. The present study used magnetic resonance imaging to investigate the distribution of HG…
• Australian older persons mental health inpatient and ambulatory services in 2015-2020 – A descriptive analysis and commentary
  November 7, 2022 by Matthew Brazel
  CONCLUSIONS: OPMHS expenditure has not increased at commensurate levels compared to other populations. The mental health of people aged over 65 appears to be a neglected policy priority in Australia. The Royal Commission into Aged Care Quality and Safety may herald service and expenditure changes.
• Cerebrospinal fluid neurofilament light and cerebral atrophy in younger-onset dementia and primary psychiatric disorders
  October 31, 2022 by Nirbaanjot Walia
  CONCLUSION: Higher CSF NfL is related to brain atrophy in YOD, further supporting its use as a nonspecific marker of neurodegeneration severity.
• Childhood trauma in patients with epileptic vs nonepileptic seizures
  October 27, 2022 by Tianren Yang
  OBJECTIVE: Childhood trauma has been implicated as a risk factor for the etiology of psychogenic nonepileptic seizures (PNES). Relatively little attention has been paid to whether profiles of specific trauma types differ between patients with epilepsy and PNES. Investigating childhood trauma profiles in these patient groups may identify psychological vulnerabilities that predispose to developing PNES, and aid early diagnoses, prevention, and treatment.
• In Vivo 7-Tesla MRI Investigation of Brain Iron and Its Metabolic Correlates in Chronic Schizophrenia
  October 26, 2022 by Parsa Ravanfar
  Brain iron is central to dopaminergic neurotransmission, a key component in schizophrenia pathology. Iron can also generate oxidative stress, which is one proposed mechanism for gray matter volume reduction in schizophrenia. The role of brain iron in schizophrenia and its potential link to oxidative stress has not been previously examined. In this study, we used 7-Tesla MRI quantitative susceptibility mapping (QSM), magnetic resonance spectroscopy (MRS), and structural T(1) imaging in 12…
• Cerebrospinal fluid neurofilament light chain differentiates behavioural variant frontotemporal dementia progressors from non-progressors
  October 6, 2022 by Dhamidhu Eratne
  CONCLUSION: This study demonstrated strong diagnostic utility of CSF NfL to distinguish bvFTD from non-progressor variants, at baseline, with high accuracy, in a real-world clinical setting. This has important clinical implications, to improve outcomes for patients and clinicians facing this challenging clinical dilemma, healthcare services, and clinical trials. Further research is required to investigate heterogeneity within the non-progressor group and potential diagnostic algorithms, and…
• Huntington's disease: Mortality and risk factors in an Australian cohort
  September 30, 2022 by Emily Sun
  CONCLUSIONS: This is the first study to examine risk factors of mortality in HD in an Australian cohort. Median survival in our cohort is consistent with previous studies in HD, and markedly reduced compared to the general Australian population. CAG repeat length was not associated with mortality suggesting that non-genetic factors contribute to mortality status and warrant further investigation.
• Neuroimaging in the Acute Psychiatric Setting: Associations With Neuropsychiatric Risk Factors
  September 21, 2022 by Katelyn Tadd
  CONCLUSIONS: Brain MRI is a useful part of psychiatric management in the presence of certain neuropsychiatric risk factors. The present findings suggest that treating teams can judiciously tailor radiological investigations while limiting excessive imaging. Future research in larger cohorts across multiple centers may contribute to shaping more consistent neuroimaging guidelines in psychiatry.

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RMH-Alfred-Concord and RANZCP VIC Section of Neuropsychiatry
Seminars in Neuropsychiatry

Dates set for 2022!

Neuropsychiatry at the Royal Melbourne, Alfred and Concord Hospitals, and the RANZCP Victorian Section of Neuropsychiatry, are pleased to have several seminars planned for 2022. Please spread the word to colleagues far and wide with this link: www.eratne.net/seminars

To receive details on how to attend sessions, for any queries, feedback, to suggest potential future topics, and to be put on the email list, please contact us.

Save the dates for these upcoming seminars, 1200-1300 (Melbourne time) on the following Tuesdays:

22 March – Dr Sarah Farrand: DBS for psychiatrists

24 May – Professor Perminder Sachdev: Tardive Dyskinesia

19 July – Cancelled

27 September – Dr Maie Walsh: Genetics and neuropsychiatric disorders

22 November – TBC

Please click here to access slides and other materials from previous seminars (for your personal use only).

Kind regards,
Dr Dhamidhu Eratne
Dr Tom Reilly
Dr Toby Winton-Brown
Dr Andrew Gleason
Professor Dennis Velakoulis

on behalf of the RANZCP Section of Neuropsychiatry Victorian Subcommittee

Contact us

Neuropsychiatry, Royal Melbourne Hospital:
Website: www.neuropsychiatry.org.au
Twitter: www.twitter.com/NWMentalHealth